RP 10 325 Pill: Oxycodone Identification, Strength and Risks

The white pill marked 10 over 325 on one side and RP on the other contains 10 mg of oxycodone hydrochloride and 325 mg of acetaminophen. Current DailyMed labeling describes it as a white to off-white, round, biconvex prescription tablet. Oxycodone is a Schedule II opioid.

Searchers often write this imprint as “RP 10 325,” “RP 10/325,” or “10 325 RP.” All refer to the same key identifying marks. The pill should not be confused with IP 204, which can contain the same active drugs and strength but has a different capsule-shaped appearance and imprint.

Appearance can identify the expected pharmaceutical product but cannot authenticate a loose tablet from an unknown source. Counterfeit pills can copy legitimate opioid markings.

RP 10 / 325 Pill Identification

What Is the RP 10 325 Pill?

RP 10/325 is an immediate-release oxycodone/acetaminophen tablet. Current labeling identifies the product as a strong prescription opioid pain medicine used when pain is severe enough to require an opioid and alternative treatments are inadequate.

“RP 10 325” is an imprint description. The active drugs are oxycodone hydrochloride 10 mg and acetaminophen 325 mg.

RP 10 / 325 vs. IP 204

This is a good example of why a pill identifier needs imprint-specific pages. Two products can contain the same drugs and strength but look quite different.

RP 5 / 325 vs. RP 7.5 / 325 vs. RP 10 / 325

The current Rhodes/Knoa labeling includes several oxycodone/acetaminophen strengths using related RP markings.

How Strong Is RP 10 325?

The tablet contains 10 mg of oxycodone hydrochloride and 325 mg of acetaminophen. The product strength is not a personal dosing recommendation.

Oxycodone effects vary with opioid tolerance, age, respiratory health, other medicines, and other substances. A person without tolerance can experience severe opioid effects from a dose that a different patient has been prescribed.

What Is Oxycodone?

Oxycodone is a semisynthetic opioid analgesic. It can reduce pain by acting at opioid receptors but can also cause euphoria, sedation, slowed breathing, constipation, tolerance, physical dependence, and opioid use disorder.

DEA classifies oxycodone as Schedule II.

Why Is Acetaminophen Added?

Acetaminophen is a non-opioid pain reliever. Each RP 10/325 tablet contains 325 mg. The combination provides two analgesic components but also means excessive tablet use can create both opioid-overdose and acetaminophen-liver risks.

FDA states that the maximum total acetaminophen amount for adults and children age 12 and older should not exceed 4,000 mg in 24 hours from all sources unless a healthcare professional directs otherwise.

What Is RP 10 325 Used For?

Current labeling states that oxycodone/acetaminophen tablets are for pain severe enough to require an opioid analgesic when alternative treatments are inadequate.

The medicine should be taken only by the person for whom it was prescribed and exactly according to the prescription.

Common Side Effects

• Drowsiness
• Dizziness
• Lightheadedness
• Nausea
• Vomiting
• Constipation
• Impaired mental or physical performance

People should not drive or perform hazardous tasks until they understand how oxycodone affects them.

RP 10 325 and Alcohol

Combining oxycodone with alcohol increases central nervous system depression. The combination can lead to profound sedation, respiratory depression, coma, and death.

RP 10 325 and Benzodiazepines

Alprazolam, clonazepam, diazepam, lorazepam, and other benzodiazepines can substantially increase the danger of an opioid. The combined effect on sedation and breathing is a major overdose concern.

Can You Overdose on RP 10 325?

Yes. Too much oxycodone can slow or stop breathing. Excessive use also increases acetaminophen exposure.

An unresponsive person with very slow breathing, stopped breathing, gurgling sounds, severe discoloration, or pinpoint pupils needs emergency help. Give naloxone if available while emergency services are being contacted.

Can RP 10 325 Cause Addiction?

Yes. Oxycodone has a high misuse and dependence potential. Signs of opioid use disorder can include craving, loss of control, continued use despite harm, using more than intended, and repeatedly obtaining tablets outside medical care.

Physical Dependence vs. Addiction

Physical dependence means the body has adapted to repeated opioid exposure and withdrawal can occur when the drug is abruptly stopped. Addiction involves a broader pattern of compulsive or poorly controlled use despite harm.

Physical dependence can occur during appropriate prescription treatment and should be managed clinically rather than interpreted automatically as addiction.

Oxycodone Withdrawal

Withdrawal can include restlessness, sweating, yawning, runny nose, watery eyes, muscle aches, anxiety, insomnia, abdominal cramps, nausea, vomiting, diarrhea, and increased heart rate.

Current opioid labeling warns against abruptly discontinuing treatment in a patient who may be physically dependent.

Can RP 10 325 Be Counterfeit?

Yes. Counterfeit pills can copy RP-style markings. Pills sold as oxycodone outside licensed pharmacies may contain unexpected substances, including illicit fentanyl.

A pill’s imprint is an identification clue, not a chemical test. The licensed pharmacy supply chain is what provides assurance about the dispensed medication.

Why Round vs. Capsule Shape Matters

RP 10/325 is round in current labeling, while IP 204 is capsule-shaped. This difference is useful when distinguishing two oxycodone/acetaminophen 10/325 products.

Shape should still be used together with the full imprint, color, and prescription information rather than as the only identifying feature.

What Should You Do if Your RP Pill Changes Appearance?

Ask the pharmacist to verify the manufacturer, NDC, and strength. Generic suppliers can change, but a legitimate pharmacy can trace exactly what it dispensed.

Treatment for Oxycodone Misuse

A person who is escalating oxycodone use, experiencing withdrawal, buying pills outside medical care, or struggling to stop can be assessed for opioid use disorder. Treatment can include buprenorphine, methadone, or naltrexone plus other medical and behavioral support.

Rehabs.Today provides resources for comparing detox centers and residential treatment programs.

Who Manufactures the RP 10 / 325 Product?

Current DailyMed labeling lists Knoa Pharma LLC as the manufacturer and Rhodes Pharmaceuticals LLC as the marketer for the reviewed RP oxycodone/acetaminophen product. Manufacturer and marketing arrangements can change, so the bottle dispensed by the pharmacy remains the best record for an individual prescription.

The durable identification facts for this article are the imprint, round shape, active ingredients, strength, and current official labeling.

Why “RP” Alone Is Not Enough to Identify the Pill

The RP product family includes more than one oxycodone/acetaminophen strength. A search for “white RP pill” can therefore be ambiguous. The numbers on the opposite face need to be read as part of the complete imprint.

Current labeling includes 5/325, 7.5/325, and 10/325 products with related RP markings. The opioid amount differs between them even though they share the same drug combination and can have similar coloring.

RP 10 325 vs. Hydrocodone 10/325

RP 10/325 contains oxycodone. M367 and IP 110 contain hydrocodone. All can pair a 10 mg opioid component with 325 mg acetaminophen, but oxycodone and hydrocodone are different drugs.

The matching “10/325” numbers should never be used as a personal opioid-conversion rule. Switching opioids requires clinical assessment and attention to tolerance and patient-specific risk.

Who May Be More Sensitive to RP 10 325?

Opioid-naive patients, older or frail adults, people with respiratory disease, and people taking other sedating medications can be more vulnerable to excessive oxycodone effects. Alcohol and benzodiazepines are particularly important because they can increase central nervous system and respiratory depression.

Liver disease and use of other acetaminophen-containing products add a separate concern. A pharmacist can help a patient identify duplicate acetaminophen across multiple prescriptions and over-the-counter medicines.

RP 10 325 During Pregnancy

Prolonged opioid use during pregnancy can cause neonatal opioid withdrawal syndrome. A newborn may require specialized assessment and treatment after delivery.

A pregnant person who has been using oxycodone regularly should not make an abrupt medication change without discussing it with the healthcare team, because physical dependence and withdrawal also need to be considered.

Can an RP 10 325 Pill Be Real but Look Slightly Different?

A legitimate pharmacy can switch generic suppliers between refills, so a patient’s oxycodone/acetaminophen tablet may not always carry the RP imprint. A change in appearance should be verified against the new prescription label or directly with the pharmacist.

That situation is different from a loose pill obtained outside pharmacy care. An unverified pill does not have a trustworthy dispensing record, even if its imprint resembles a known product.

How Long Can Oxycodone Be Detected?

Drug-test detection depends on the test, cutoff, dose, frequency of use, metabolism, and time since exposure. A detection window should not be confused with the duration of pain relief or sedation.

Someone who needs a definitive interpretation for employment, medical, legal, or treatment purposes should rely on the testing laboratory or clinician rather than a single generic online timetable.

Safe Storage and Disposal of RP 10 325

Keep Schedule II opioids in a secure location that children, visitors, and other household members cannot access. Do not share leftover medication or save it for another person’s future pain.

Use an authorized medication take-back program for unwanted tablets whenever possible. If one is unavailable, follow current FDA instructions for opioid disposal.

When Is RP 10 325 a Medical Emergency?

Call emergency services when a person cannot be awakened, has very slow or stopped breathing, collapses, develops severe confusion, or may have taken a counterfeit opioid. Naloxone should be given when available if opioid overdose is suspected.

Frequently Asked Questions About RP 10 325

What pill has RP and 10 325 on it?

Current DailyMed labeling identifies the white-to-off-white round tablet as oxycodone hydrochloride 10 mg / acetaminophen 325 mg.

Is RP 10 325 Percocet?

It contains the oxycodone/acetaminophen drug combination associated with Percocet, but the RP tablet is a generic product.

Is RP 10 325 the same as IP 204?

They contain the same labeled active drugs and strength, but they are different manufactured tablets with different imprints and shapes.

Is RP 10 325 Schedule II?

Yes. Oxycodone is a Schedule II controlled substance.

Can RP 10 325 cause withdrawal?

Yes. Repeated oxycodone use can cause physical dependence, and abrupt discontinuation can trigger opioid withdrawal.

Can a fake pill have RP 10 325 on it?

Yes. Counterfeit opioid tablets can imitate legitimate markings.

Sources

• DailyMed: Oxycodone and Acetaminophen Tablets, IP 204 — current Amneal labeling, identification and safety information.
• DailyMed: Oxycodone and Acetaminophen Tablets, RP Imprints — current Rhodes/Knoa labeling, identification and safety information.
• Drug Enforcement Administration: Drug Scheduling — current Schedule II status of oxycodone.
• U.S. Food and Drug Administration: Acetaminophen — total daily acetaminophen safety information.
• U.S. Food and Drug Administration: Counterfeit Medicine — counterfeit prescription-drug risks.
• Centers for Disease Control and Prevention: Overdose Prevention — opioid overdose recognition and naloxone information.
• SAMHSA: Substance Use Treatment Options — evidence-based opioid use disorder treatment options.